STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (302 aa)    
Predicted Functional Partners:
ABK61388.1
O-acetylhomoserine/O-acetylserine sulfhydrylase; Identified by match to protein family HMM PF01053; match to protein family HMM TIGR01326.
 
 
 0.994
ABK60718.1
Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.
  
 
 0.943
hisF
Imidazole glycerol phosphate synthase subunit HisF; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family.
  
    0.933
ABK60927.1
Aspartate kinase, putative; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.
 
  
 0.896
ABK61675.1
5-methyltetrahydrofolate--homocysteine methyltransferase, putative; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.
  
  
 0.852
ABK62048.1
Pyridine nucleotide-disulphide oxidoreductase family protein; Identified by match to protein family HMM PF00070; match to protein family HMM PF00581; match to protein family HMM PF02852.
   
    0.838
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.827
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
  0.815
sdaAA
L-serine dehydratase, iron-sulfur-dependent, alpha subunit; Identified by match to protein family HMM PF03313; match to protein family HMM TIGR00718; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.809
sdaAB
L-serine dehydratase, iron-sulfur-dependent, beta subunit; Identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.809
Your Current Organism:
Clostridium novyi
NCBI taxonomy Id: 386415
Other names: C. novyi NT, Clostridium novyi NT, Clostridium novyi str. NT, Clostridium novyi strain NT, Clostridium novyi-NT
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