STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutS2DNA mismatch repair MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (785 aa)    
Predicted Functional Partners:
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
 
0.932
ABK61455.1
Protease; Identified by match to protein family HMM PF01136.
  
    0.851
ABK60421.1
Conserved hypothetical protein; Identified by match to protein family HMM PF04463.
       0.799
ABK61463.1
Identified by match to protein family HMM PF05670; match to protein family HMM PF05833.
 
     0.744
polA
DNA polymerase I, polA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.704
rpsU
Ribosomal protein S21; Identified by match to protein family HMM PF01165; match to protein family HMM TIGR00030; Belongs to the bacterial ribosomal protein bS21 family.
 
 
   0.646
mutL
DNA mismatch repair protein hexb; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
  
 0.634
rplY-2
Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
       0.632
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
  
 
   0.630
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
    
   0.618
Your Current Organism:
Clostridium novyi
NCBI taxonomy Id: 386415
Other names: C. novyi NT, Clostridium novyi NT, Clostridium novyi str. NT, Clostridium novyi strain NT, Clostridium novyi-NT
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.