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purE protein (Sulfurovum sp. NBC371) - STRING interaction network
"purE" - N5-carboxyaminoimidazole ribonucleotide mutase in Sulfurovum sp. NBC371
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (164 aa)    
Predicted Functional Partners:
purM
annotation not available (331 aa)
 
 
  0.995
purC
annotation not available (244 aa)
 
  0.993
purD
annotation not available (422 aa)
   
  0.988
purH
Bifunctional purine biosynthesis protein PurH; Bifunctional enzyme, phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (510 aa)
 
   
  0.944
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family (456 aa)
 
   
  0.944
purT
Formate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family (387 aa)
 
   
  0.881
purN
annotation not available (184 aa)
 
   
  0.880
SUN_0355
annotation not available (446 aa)
   
        0.870
purQ
Phosphoribosylformylglycinamidine synthase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (223 aa)
 
   
  0.834
trpF
annotation not available (196 aa)
   
   
  0.814
Your Current Organism:
Sulfurovum sp. NBC371
NCBI taxonomy Id: 387093
Other names: S. sp. NBC37-1, Sulfurovum sp. NBC37-1, Sulfurovum sp. NBC371
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