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nudH protein (Sulfurovum sp. NBC371) - STRING interaction network
"nudH" - RNA pyrophosphohydrolase in Sulfurovum sp. NBC371
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nudHRNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5’-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (157 aa)    
Predicted Functional Partners:
SUN_1460
annotation not available (455 aa)
       
  0.816
SUN_0458
annotation not available (205 aa)
 
      0.794
SUN_0457
annotation not available (181 aa)
 
          0.781
SUN_0456
Aspartokinase; Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family (401 aa)
         
  0.770
SUN_0454
Oxygen-independent coproporphyrinogen-III oxidase-like protein; Involved in the biosynthesis of porphyrin-containing compound (353 aa)
              0.666
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA (89 aa)
   
 
  0.609
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (898 aa)
         
  0.602
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (481 aa)
   
   
  0.602
rplW
50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (93 aa)
   
 
  0.598
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine (248 aa)
   
 
  0.593
Your Current Organism:
Sulfurovum sp. NBC371
NCBI taxonomy Id: 387093
Other names: S. sp. NBC37-1, Sulfurovum sp. NBC37-1, Sulfurovum sp. NBC371
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