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thiC protein (Sulfurovum sp. NBC371) - STRING interaction network
"thiC" - Thiamine biosynthesis protein ThiC in Sulfurovum sp. NBC371
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (629 aa)    
Predicted Functional Partners:
thiD
Phosphomethylpyrimidine kinase (270 aa)
 
 
  0.998
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (270 aa)
 
  0.976
thiE
Thiamine-phosphate pyrophosphorylase (210 aa)
 
 
  0.968
SUN_1198
Thiamine monophosphate kinase (273 aa)
       
  0.911
mqnC
Hypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) (351 aa)
   
 
  0.835
mqnE
Hypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1- carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate (357 aa)
   
 
  0.835
purM
Phosphoribosylaminoimidazole synthetase (331 aa)
       
  0.819
thiS
Thiamine biosynthesis protein ThiS (66 aa)
   
   
  0.801
thiO
Thiamine biosynthesis protein ThiO (373 aa)
         
  0.743
cysN
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity (479 aa)
     
 
    0.720
Your Current Organism:
Sulfurovum sp. NBC371
NCBI taxonomy Id: 387093
Other names: S. sp. NBC37-1, Sulfurovum, Sulfurovum Inagaki et al. 2004, Sulfurovum NBC37_1, Sulfurovum sp. NBC37-1, Sulfurovum sp. NBC371
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