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ychF protein (Sulfurovum sp. NBC371) - STRING interaction network
"ychF" - GTP-dependent nucleic acid-binding protein EngD in Sulfurovum sp. NBC371
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ychFGTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner (367 aa)    
Predicted Functional Partners:
rplI
50S ribosomal protein L9; Binds to the 23S rRNA (147 aa)
   
  0.863
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (181 aa)
   
 
  0.857
rplY
50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (178 aa)
   
 
  0.844
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (155 aa)
   
 
  0.844
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center (178 aa)
   
 
  0.843
rplA
50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (234 aa)
   
 
  0.839
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (232 aa)
   
 
  0.838
rpsB
30S ribosomal protein S2 (344 aa)
   
 
  0.836
rplC
50S ribosomal protein L3 (193 aa)
   
 
  0.834
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA (127 aa)
   
 
    0.832
Your Current Organism:
Sulfurovum sp. NBC371
NCBI taxonomy Id: 387093
Other names: S. sp. NBC37-1, Sulfurovum, Sulfurovum Inagaki et al. 2004, Sulfurovum NBC37_1, Sulfurovum sp. NBC37-1, Sulfurovum sp. NBC371
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