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hisB protein (Sulfurovum sp. NBC371) - STRING interaction network
"hisB" - Imidazoleglycerol-phosphate dehydratase in Sulfurovum sp. NBC371
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hisBImidazoleglycerol-phosphate dehydratase (190 aa)    
Predicted Functional Partners:
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (254 aa)
 
 
  0.999
hisH
Amidotransferase HisH (EC-2.4.2.-); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (203 aa)
 
 
  0.999
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (430 aa)
 
  0.998
hisC
Histidinol-phosphate aminotransferase (364 aa)
 
  0.998
hisI
Histidine biosynthesis bifunctional protein HisI (222 aa)
 
 
  0.994
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (EC-5.3.1.16) (237 aa)
 
   
  0.970
hisG
ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (206 aa)
 
   
  0.960
SUN_1226
YrbI family phosphatase (165 aa)
              0.883
SUN_1225
Hypothetical protein (170 aa)
              0.859
SUN_1228
Hypothetical protein (261 aa)
              0.859
Your Current Organism:
Sulfurovum sp. NBC371
NCBI taxonomy Id: 387093
Other names: S. sp. NBC37-1, Sulfurovum, Sulfurovum Inagaki et al. 2004, Sulfurovum NBC37_1, Sulfurovum sp. NBC37-1, Sulfurovum sp. NBC371
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