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thiI protein (Sulfurovum sp. NBC371) - STRING interaction network
"thiI" - Thiamin biosynthesis protein ThiI in Sulfurovum sp. NBC371
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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thiIThiamin biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (486 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase (400 aa)
   
  0.993
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (270 aa)
   
 
  0.954
SUN_1787
ThiF/MoeB/HesA family protein (231 aa)
   
 
  0.913
SUN_0111
Molybdenum cofactor biosynthesis protein E (144 aa)
   
  0.899
SUN_0110
Molybdenum cofactor biosynthesis protein D (73 aa)
     
  0.859
thiE
Thiamine-phosphate pyrophosphorylase (210 aa)
   
 
  0.801
metH
5-methyltetrahydrofolate--homocysteine methyltransferase (1169 aa)
       
  0.797
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (542 aa)
   
 
  0.771
mnmA
tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (340 aa)
 
   
  0.749
SUN_0295
Hypothetical protein (188 aa)
       
  0.737
Your Current Organism:
Sulfurovum sp. NBC371
NCBI taxonomy Id: 387093
Other names: S. sp. NBC37-1, Sulfurovum, Sulfurovum Inagaki et al. 2004, Sulfurovum NBC37_1, Sulfurovum sp. NBC37-1, Sulfurovum sp. NBC371
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