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hisD protein (Sulfurovum sp. NBC371) - STRING interaction network
"hisD" - Histidinol dehydrogenase in Sulfurovum sp. NBC371
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (430 aa)    
Predicted Functional Partners:
hisC
Histidinol-phosphate aminotransferase (364 aa)
  0.998
hisB
Imidazoleglycerol-phosphate dehydratase (190 aa)
 
  0.998
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (254 aa)
 
 
  0.995
hisI
Histidine biosynthesis bifunctional protein HisI (222 aa)
   
  0.995
SUN_0354
PHP family histidinol phosphatase/hydrolase (263 aa)
   
 
  0.987
hisG
ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (206 aa)
 
   
  0.986
hisH
Amidotransferase HisH (EC-2.4.2.-); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (203 aa)
 
   
  0.984
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (EC-5.3.1.16) (237 aa)
 
   
  0.962
SUN_1940
HAD-superfamily hydrolase (149 aa)
   
 
  0.916
SUN_0880
Histidine decarboxylase (311 aa)
         
    0.900
Your Current Organism:
Sulfurovum sp. NBC371
NCBI taxonomy Id: 387093
Other names: S. sp. NBC37-1, Sulfurovum, Sulfurovum Inagaki et al. 2004, Sulfurovum NBC37_1, Sulfurovum sp. NBC37-1, Sulfurovum sp. NBC371
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