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hisH protein (Sulfurovum sp. NBC371) - STRING interaction network
"hisH" - Amidotransferase HisH in Sulfurovum sp. NBC371
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisHAmidotransferase HisH (EC-2.4.2.-); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (203 aa)    
Predicted Functional Partners:
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (254 aa)
  0.999
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (EC-5.3.1.16) (237 aa)
 
  0.999
hisB
Imidazoleglycerol-phosphate dehydratase (190 aa)
 
 
  0.999
hisI
Histidine biosynthesis bifunctional protein HisI (222 aa)
 
 
  0.997
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (430 aa)
 
   
  0.984
hisG
ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (206 aa)
 
   
  0.969
hisC
Histidinol-phosphate aminotransferase (364 aa)
 
 
  0.926
purH
Bifunctional purine biosynthesis protein PurH (EC-2.1.2.3 3.5.4.10) (510 aa)
   
 
  0.911
SUN_1940
HAD-superfamily hydrolase (149 aa)
   
 
  0.891
SUN_2371
Adenylosuccinate lyase (443 aa)
   
 
    0.834
Your Current Organism:
Sulfurovum sp. NBC371
NCBI taxonomy Id: 387093
Other names: S. sp. NBC37-1, Sulfurovum, Sulfurovum Inagaki et al. 2004, Sulfurovum NBC37_1, Sulfurovum sp. NBC37-1, Sulfurovum sp. NBC371
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