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hisA protein (Sulfurovum sp. NBC371) - STRING interaction network
"hisA" - Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide in Sulfurovum sp. NBC371
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hisAPhosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (EC-5.3.1.16) (237 aa)    
Predicted Functional Partners:
hisI
Histidine biosynthesis bifunctional protein HisI (222 aa)
 
  0.999
hisH
Amidotransferase HisH (EC-2.4.2.-); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (203 aa)
 
  0.999
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (254 aa)
 
 
0.997
hisG
ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (206 aa)
 
 
  0.981
hisB
Imidazoleglycerol-phosphate dehydratase (190 aa)
 
   
  0.970
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (430 aa)
 
   
  0.962
SUN_1954
CDP-diacylglycerol--serine O-phosphatidyltransferase (239 aa)
              0.906
hisC
Histidinol-phosphate aminotransferase (364 aa)
 
   
  0.893
SUN_1695
Indole-3-glycerol-phosphate synthase (264 aa)
   
 
  0.893
ftsH
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (671 aa)
   
        0.886
Your Current Organism:
Sulfurovum sp. NBC371
NCBI taxonomy Id: 387093
Other names: S. sp. NBC37-1, Sulfurovum, Sulfurovum Inagaki et al. 2004, Sulfurovum NBC37_1, Sulfurovum sp. NBC37-1, Sulfurovum sp. NBC371
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