node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SUN_0471 | SUN_0539 | SUN_0471 | SUN_0539 | Anthranilate synthase component I. | Anthranilate synthase component II. | 0.999 |
SUN_0471 | SUN_2069 | SUN_0471 | SUN_2069 | Anthranilate synthase component I. | Aminodeoxychorismate synthase subunit I. | 0.854 |
SUN_0471 | aroB | SUN_0471 | SUN_1010 | Anthranilate synthase component I. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.486 |
SUN_0471 | aroC | SUN_0471 | SUN_2260 | Anthranilate synthase component I. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.959 |
SUN_0471 | aroE | SUN_0471 | SUN_0470 | Anthranilate synthase component I. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.875 |
SUN_0471 | mqnA | SUN_0471 | SUN_0109 | Anthranilate synthase component I. | Conserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.800 |
SUN_0471 | pheA | SUN_0471 | SUN_2057 | Anthranilate synthase component I. | Chorismate mutase/prephenate dehydratase; Bifunctional enzyme. | 0.957 |
SUN_0471 | trpA | SUN_0471 | SUN_2098 | Anthranilate synthase component I. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.946 |
SUN_0539 | SUN_0471 | SUN_0539 | SUN_0471 | Anthranilate synthase component II. | Anthranilate synthase component I. | 0.999 |
SUN_0539 | SUN_2069 | SUN_0539 | SUN_2069 | Anthranilate synthase component II. | Aminodeoxychorismate synthase subunit I. | 0.999 |
SUN_0539 | aroA | SUN_0539 | SUN_0549 | Anthranilate synthase component II. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.447 |
SUN_0539 | aroB | SUN_0539 | SUN_1010 | Anthranilate synthase component II. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.636 |
SUN_0539 | aroC | SUN_0539 | SUN_2260 | Anthranilate synthase component II. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.962 |
SUN_0539 | aroE | SUN_0539 | SUN_0470 | Anthranilate synthase component II. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.584 |
SUN_0539 | mqnA | SUN_0539 | SUN_0109 | Anthranilate synthase component II. | Conserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.805 |
SUN_0539 | pheA | SUN_0539 | SUN_2057 | Anthranilate synthase component II. | Chorismate mutase/prephenate dehydratase; Bifunctional enzyme. | 0.957 |
SUN_0539 | trpA | SUN_0539 | SUN_2098 | Anthranilate synthase component II. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.951 |
SUN_1998 | aroA | SUN_1998 | SUN_0549 | Prephenate dehydrogenase; C terminus of bifunctional TyrA protein, chorismate mutase T EC 5.4.99.5, N-terminal and prephenate dehydrogenase EC 1.3.1.12], C-terminal. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.975 |
SUN_1998 | aroB | SUN_1998 | SUN_1010 | Prephenate dehydrogenase; C terminus of bifunctional TyrA protein, chorismate mutase T EC 5.4.99.5, N-terminal and prephenate dehydrogenase EC 1.3.1.12], C-terminal. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.766 |
SUN_1998 | aroC | SUN_1998 | SUN_2260 | Prephenate dehydrogenase; C terminus of bifunctional TyrA protein, chorismate mutase T EC 5.4.99.5, N-terminal and prephenate dehydrogenase EC 1.3.1.12], C-terminal. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.841 |