STRINGSTRING
SUN_2288 protein (Sulfurovum sp. NBC371) - STRING interaction network
"SUN_2288" - Thymidylate synthase, flavin-dependent in Sulfurovum sp. NBC371
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
SUN_2288Thymidylate synthase, flavin-dependent (274 aa)    
Predicted Functional Partners:
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (191 aa)
   
 
  0.993
SUN_1566
dUTP diphosphatase (226 aa)
       
    0.977
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (416 aa)
       
  0.947
folD
Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (281 aa)
       
  0.911
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) (278 aa)
         
  0.910
metH
5-methyltetrahydrofolate--homocysteine methyltransferase (1169 aa)
         
  0.900
SUN_2036
5’-nucleotidase (518 aa)
       
    0.900
purH
Bifunctional purine biosynthesis protein PurH (EC-2.1.2.3 3.5.4.10) (510 aa)
       
    0.900
purN
Phosphoribosylglycinamide formyltransferase (184 aa)
       
    0.900
fmt
methionyl-tRNA formyltransferase; Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by- (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (304 aa)
         
    0.900
Your Current Organism:
Sulfurovum sp. NBC371
NCBI taxonomy Id: 387093
Other names: S. sp. NBC37-1, Sulfurovum, Sulfurovum Inagaki et al. 2004, Sulfurovum NBC37_1, Sulfurovum sp. NBC37-1, Sulfurovum sp. NBC371
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