node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SUN_0014 | def | SUN_0014 | SUN_0013 | Mg chelatase-related protein. | Formylmethionine deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.722 |
SUN_0014 | ruvC | SUN_0014 | SUN_2466 | Mg chelatase-related protein. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.698 |
SUN_0187 | dnaE | SUN_0187 | SUN_0567 | ATP-dependent DNA helicase, UvrD/REP family; Belongs to the helicase family. UvrD subfamily. | DNA polymerase III, alpha subunit. | 0.571 |
SUN_0187 | polA | SUN_0187 | SUN_1315 | ATP-dependent DNA helicase, UvrD/REP family; Belongs to the helicase family. UvrD subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.532 |
SUN_0187 | recA | SUN_0187 | SUN_0082 | ATP-dependent DNA helicase, UvrD/REP family; Belongs to the helicase family. UvrD subfamily. | DNA recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.522 |
SUN_0187 | ruvC | SUN_0187 | SUN_2466 | ATP-dependent DNA helicase, UvrD/REP family; Belongs to the helicase family. UvrD subfamily. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.468 |
def | SUN_0014 | SUN_0013 | SUN_0014 | Formylmethionine deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Mg chelatase-related protein. | 0.722 |
def | ruvC | SUN_0013 | SUN_2466 | Formylmethionine deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.472 |
dnaE | SUN_0187 | SUN_0567 | SUN_0187 | DNA polymerase III, alpha subunit. | ATP-dependent DNA helicase, UvrD/REP family; Belongs to the helicase family. UvrD subfamily. | 0.571 |
dnaE | polA | SUN_0567 | SUN_1315 | DNA polymerase III, alpha subunit. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.640 |
dnaE | recA | SUN_0567 | SUN_0082 | DNA polymerase III, alpha subunit. | DNA recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.460 |
dnaE | ruvA | SUN_0567 | SUN_0823 | DNA polymerase III, alpha subunit. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.409 |
dnaE | ruvC | SUN_0567 | SUN_2466 | DNA polymerase III, alpha subunit. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.476 |
msrA-2 | polA | SUN_2465 | SUN_1315 | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.887 |
msrA-2 | ruvC | SUN_2465 | SUN_2466 | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.496 |
polA | SUN_0187 | SUN_1315 | SUN_0187 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | ATP-dependent DNA helicase, UvrD/REP family; Belongs to the helicase family. UvrD subfamily. | 0.532 |
polA | dnaE | SUN_1315 | SUN_0567 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA polymerase III, alpha subunit. | 0.640 |
polA | msrA-2 | SUN_1315 | SUN_2465 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.887 |
polA | recA | SUN_1315 | SUN_0082 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.996 |
polA | recJ | SUN_1315 | SUN_0004 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Single-strand DNA-specific exonuclease. | 0.584 |