node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LVIS_0682 | murB | LVIS_0682 | LVIS_0681 | NhaP-type Na+/H+ and K+/H+ antiporter. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.752 |
ddl | mraY | LVIS_1268 | LVIS_1451 | D-alanine--D-alanine ligase; Cell wall formation. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.562 |
ddl | murA | LVIS_1268 | LVIS_0494 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.705 |
ddl | murA-2 | LVIS_1268 | LVIS_1276 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.750 |
ddl | murB | LVIS_1268 | LVIS_0681 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.960 |
ddl | murC | LVIS_1268 | LVIS_1047 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.972 |
ddl | murD | LVIS_1268 | LVIS_1450 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.735 |
ddl | murE | LVIS_1268 | LVIS_0070 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.577 |
ddl | murF | LVIS_1268 | LVIS_0503 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.993 |
ddl | murG | LVIS_1268 | LVIS_1449 | D-alanine--D-alanine ligase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.697 |
mraY | ddl | LVIS_1451 | LVIS_1268 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | D-alanine--D-alanine ligase; Cell wall formation. | 0.562 |
mraY | murA | LVIS_1451 | LVIS_0494 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.791 |
mraY | murA-2 | LVIS_1451 | LVIS_1276 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.777 |
mraY | murB | LVIS_1451 | LVIS_0681 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.774 |
mraY | murC | LVIS_1451 | LVIS_1047 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.878 |
mraY | murD | LVIS_1451 | LVIS_1450 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.982 |
mraY | murE | LVIS_1451 | LVIS_0070 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.797 |
mraY | murF | LVIS_1451 | LVIS_0503 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.987 |
mraY | murG | LVIS_1451 | LVIS_1449 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.994 |
murA | ddl | LVIS_0494 | LVIS_1268 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | D-alanine--D-alanine ligase; Cell wall formation. | 0.705 |