STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LVIS_1882Fe2+/Zn2+ uptake regulation protein; Belongs to the Fur family. (163 aa)    
Predicted Functional Partners:
sigA
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.538
LVIS_0086
Peroxiredoxin.
  
  
 0.528
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.491
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
 
    0.482
LVIS_0924
Biotin operon repressor.
     
 0.475
LVIS_1881
Uncharacterized membrane protein.
       0.473
rpoA
DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.472
LVIS_1880
Uncharacterized membrane protein.
       0.466
LVIS_0471
ABC-type Mn/Zn transport system, ATPase component.
  
  
 0.409
rpoB
DNA-directed RNA polymerase, beta subunit/140 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.401
Your Current Organism:
Lactobacillus brevis
NCBI taxonomy Id: 387344
Other names: L. brevis ATCC 367, Lactobacillus brevis ATCC 367, Lactobacillus brevis str. ATCC 367, Lactobacillus brevis strain ATCC 367
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.