STRINGSTRING
NORK protein (Medicago truncatula) - STRING interaction network
"NORK" - Nodulation receptor kinase in Medicago truncatula
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NORKNodulation receptor kinase; Involved in the perception of symbiotic fungi and bacteria. Part of the perception/transduction system leading to nodulation or mycorrhizal infection. Phosphorylates PUB1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family (924 aa)    
Predicted Functional Partners:
DMI1
Ion channel DMI1; Required for early signal transduction events leading to endosymbiosis. Acts early in a signal transduction chain leading from the perception of Nod factor to the activation of calcium spiking. Also involved in mycorrhizal symbiosis. May be involved in the regulation of the calcium channel responsible for calcium spiking by mobilizing another cation, and thereby altering the membrane potential (882 aa)
           
  0.808
11416675
Calreticulin; Uncharacterized protein (423 aa)
           
  0.591
IPD3
CYCLOPS; Interacting protein of DMI3 (513 aa)
     
   
  0.563
NSP2
Nodulation-signaling pathway 2 protein; Transcriptional regulator essential for Nod-factor- induced gene expression. Acts downstream of calcium spiking and DMI3, a calcium/calmodulin-dependent protein kinase (CCaMK); Belongs to the GRAS family (508 aa)
     
   
  0.558
NIN
Nodule inception protein (933 aa)
           
  0.539
11444791
EF hand calcium-binding family protein; Calmodulin (164 aa)
           
  0.536
11431828
EF hand calcium-binding family protein; Calmodulin; Calmodulin 2; Uncharacterized protein (149 aa)
           
  0.536
11413560
EF hand calcium-binding family protein; Calmodulin (266 aa)
           
  0.536
11445057
EF hand calcium-binding family protein; Calmodulin (236 aa)
           
  0.536
11425680
Calmodulin (149 aa)
           
  0.536
Your Current Organism:
Medicago truncatula
NCBI taxonomy Id: 3880
Other names: M. truncatula, Medicago truncatula, Medicago truncatula Gaertn., barrel medic
Server load: low (14%) [HD]