STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
whiAConserved hypothetical protein; Involved in cell division and chromosome segregation. (303 aa)    
Predicted Functional Partners:
SSA_0811
Conserved hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
  
  
 0.931
SSA_0810
P-loop ATPase, putative; Displays ATPase and GTPase activities.
 
  
 0.893
ylxM
Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
  
 0.738
SSA_1417
SAM-dependent methyltransferase, putative; GC: 48.55%; Codon Adaptation Index (CAI): 0.781; Protein involved in transferase activity.
  
     0.666
SSA_2241
Conserved uncharacterized protein; GC: 41.95%; Codon Adaptation Index (CAI): 0.781. Curator(s): J. Alves; Protein involved in molecular function unknown; Belongs to the UPF0297 family.
  
     0.665
SSA_0809
Translation initiation inhibitor, yjgF family / endoribonuclease L-PSP, putative; GC: 44.36%; Codon Adaptation Index (CAI): 0.797. Highly conserved, active on single-stranded mRNA. Curator(s): X. Ge, J. Alves.
       0.650
polC
DNA polymerase III polC-type, putative; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
     0.625
asp
Alkaline-shock protein, putative; GC: 39.34%; Codon Adaptation Index (CAI): 0.797. Curator(s): J. Alves.
  
     0.535
pkn
Serine/threonine protein kinase, putative; GC: 45.95%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.786; Protein involved in transferase activity.
 
   
 0.523
folK
Bifunctional folate synthesis protein, putative; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
   
    0.521
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.