STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
enoEnolase, putative; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa)    
Predicted Functional Partners:
pykF
Pyruvate kinase I, fructose-stimulated, putative; GC: 42.36%; Codon Adaptation Index (CAI): 0.802. Curator(s): L. Ozaki; Protein involved in transferase activity and glycolysis; Belongs to the pyruvate kinase family.
 
 0.992
pgk
Phosphoglycerate kinase, putative; GC: 43.27%; Codon Adaptation Index (CAI): 0.793. Curator(s): P. Manque; Protein involved in transferase activity; Belongs to the phosphoglycerate kinase family.
 
 
 0.991
pgi
Glucose-6-phosphate isomerase, putative; GC: 41.79%; Codon Adaptation Index (CAI): 0.77; Belongs to the GPI family.
  
 0.982
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, putative; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.980
gapA
Glyceraldehyde 3-phosphate dehydrogenase, putative; GC: 42.36%; Codon Adaptation Index (CAI): 0.806; Protein involved in NAD binding; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 
 0.977
fba
Fructose-bisphosphate aldolase, putative; GC: 44.33%; Codon Adaptation Index (CAI): 0.763; Protein involved in fructose 1,6-bisphosphate metabolism.
  
 0.968
tpi
Triosephosphate isomerase, putative; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.963
tkt
Transketolase, putative; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 0.933
ppc
Phosphoenolpyruvate carboxylase, putative; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
   
 
 0.929
rplD
50S ribosomal protein L4, putative; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
 0.917
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.