STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSA_1057Aminotransferase, class-V, putative; GC: 45.06%; Codon Adaptation Index (CAI): 0.745; Protein involved in transaminase activity and transferase activity. (380 aa)    
Predicted Functional Partners:
thiI
Thiamine biosynthesis protein, putative; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 0.993
nifU
NifU family protein, putative; GC: 48.63%; Codon Adaptation Index (CAI): 0.757.
 
 0.993
SSA_1213
Pyridoxal-phosphate dependent aminotransferase, putative; GC: 42.74%; Codon Adaptation Index (CAI): 0.761; Protein involved in transferase activity.
  
  
 
0.915
SSA_1059
Conserved hypothetical protein; GC: 35.82%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.773. SignalP prediction: Yes (prob. 0.593).
  
    0.730
dnaK
Chaperone protein dnaK/HSP70, putative; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
  
 0.656
SSA_1586
Conserved hypothetical protein; GC: 48.79%; Codon Adaptation Index (CAI): 0.802. Helix-turn-helix prediction: AraC; Protein involved in molecular function unknown and regulation of transcription, DNA-dependent.
  
  
 0.612
acp
Acyl carrier protein, putative; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
    
 
 0.548
acpP
Acyl carrier protein, putative; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
    
 
 0.548
dltC
D-alanyl carrier protein, putative; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
    
 
 0.548
fbp
Firmicute fructose-1,6-bisphosphatase, putative; GC: 44.85%; Codon Adaptation Index (CAI): 0.784. Curator(s): J. Alves; Protein involved in hydrolase activity and fructose-bisphosphatase activity.
       0.539
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.