STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppcPhosphoenolpyruvate carboxylase, putative; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (948 aa)    
Predicted Functional Partners:
eno
Enolase, putative; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.929
pykF
Pyruvate kinase I, fructose-stimulated, putative; GC: 42.36%; Codon Adaptation Index (CAI): 0.802. Curator(s): L. Ozaki; Protein involved in transferase activity and glycolysis; Belongs to the pyruvate kinase family.
     
 0.927
SSA_1053
Pyruvate phosphate dikinase, putative; GC: 47.56%; Transporter classification TC:8.A.7.1.1. Codon Adaptation Index (CAI): 0.775. Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in pyruvate, phosphate dikinase activity.
     
 0.907
SSA_0703
Citrate synthase, putative; GC: 46.92%; Codon Adaptation Index (CAI): 0.773. Curator(s): P. Xu; Protein involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer; Belongs to the citrate synthase family.
     
 0.855
ftsW
Cell division protein FtsW, putative; GC: 44.2%; Transporter classification TC:9.B.3.1.3. Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.729. SignalP prediction: Yes (prob. 0.95); Protein involved in cell division; Belongs to the SEDS family.
       0.673
pepV
Dipeptidase V, putative; GC: 43.62%; Codon Adaptation Index (CAI): 0.789; Protein involved in metallopeptidase activity.
  
  
 0.588
tuf
Elongation factor Tu, putative; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
     
 0.573
pepQ
Proline dipeptidase, putative; GC: 46.17%; Codon Adaptation Index (CAI): 0.806; Protein involved in metalloexopeptidase activity and dipeptidase activity.
   
  
 0.568
pepN
Aminopeptidase N, putative; GC: 45.38%; Codon Adaptation Index (CAI): 0.804. Curator(s): T. Kitten.
 
   
 0.559
tpi
Triosephosphate isomerase, putative; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.535
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.