STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacCTagatose-6-phosphate kinase, putative; GC: 41.72%; Codon Adaptation Index (CAI): 0.773. Curator(s): J. Alves; Protein involved in lactose catabolism via tagatose-6-phosphate; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (309 aa)    
Predicted Functional Partners:
lacB
Galactose-6-phosphate isomerase, LacB subunit, putative; GC: 39.15%; Codon Adaptation Index (CAI): 0.818; Protein involved in intramolecular oxidoreductase activity, interconverting aldoses and ketoses and galactose-6-phosphate isomerase activity.
  
 
 0.994
lacD
Tagatose 1,6-diphosphate aldolase 2, putative; GC: 45.97%; Codon Adaptation Index (CAI): 0.791; Belongs to the aldolase LacD family.
 
 
 0.993
lacA
Conserved hypothetical protein; GC: 45.83%; Codon Adaptation Index (CAI): 0.805.
  
 
 0.993
fruA
PTS system, fructose specific II ABC components, putative; GC: 43.96%; Transporter classification TC:4.A.2.1.3. Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.786.
 
  
 0.991
lacD-2
Tagatose 1,6-diphosphate aldolase, putative; GC: 50.19%; Codon Adaptation Index (CAI): 0.765. Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in lactose catabolism via tagatose-6-phosphate; Belongs to the aldolase LacD family.
 
 
 0.971
lacE
Phosphotransferase system lactose-specific component IIBC, putative; GC: 45.28%; Transporter classification TC:4.A.3.1.1. Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.776. Curator(s): J. Alves.
 
  
 0.923
pfk
6-phosphofructokinase, putative; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
 0.915
lacR
Transcriptional repressor of sugar metabolism, GlpR/DeoR family, putative; GC: 44.58%; Codon Adaptation Index (CAI): 0.797. Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in transferase activity, pentose-phosphate shunt, non-oxidative branch and regulation of transcription, DNA-dependent.
 
  
 0.831
lacF
PTS system, lactose-specific IIA component, putative; GC: 44.34%; Transporter classification TC:4.A.3.1.1. Codon Adaptation Index (CAI): 0.761.
  
  
 0.767
SSA_0707
Lactose phosphotransferase system transcriptional repressor, putative; GC: 41.9%; Codon Adaptation Index (CAI): 0.788. Curator(s): P. Xu, J. Alves; Protein involved in transferase activity.
 
  
 0.705
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.