STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
czcDCation (Co/Zn/Cd) efflux protein, putative; GC: 45.78%; Transporter classification TC:2.A.4.1.3. Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.773. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.997); Curator(s): J. Alves. (291 aa)    
Predicted Functional Partners:
SSA_2322
Transcriptional regulator, TetR/AcrR family, putative; GC: 44.06%; Codon Adaptation Index (CAI): 0.789. Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in regulation of transcription.
       0.574
ctpA
Copper-translocating P-type ATPase, putative; GC: 47.93%; Transporter classification TC:3.A.3.5.1. Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.753. LipoP prediction: SpI. Helix-turn-helix prediction: AraC. Curator(s): M. Serrano; Protein involved in metal ion transporter activity.
  
  
 0.566
SSA_1413
GufA-like protein, putative; GC: 50.42%; Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.743; Protein involved in metal ion transporter activity and cytochrome complex assembly.
 
 
 0.537
carB
Carbamoyl-phosphate synthase large chain, putative; GC: 49.5%; Codon Adaptation Index (CAI): 0.783; Protein involved in metal ion binding.
      
 0.534
SSA_0851
Cation efflux family protein, putative; GC: 45.51%; Transporter classification TC:2.A.4.1.5. Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.76. Curator(s): L. Ozaki; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
 
 
 0.514
SSA_2323
Transporter, putative; GC: 48.24%; Transmembrane domains: 12. Codon Adaptation Index (CAI): 0.751. SignalP prediction: Yes (prob. 0.983).
       0.464
polA
DNA polymerase I - 3'-5' exonuclease and polymerase domains, putative; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
    0.451
ssaB
Manganese/Zinc ABC transporter substrate-binding lipoprotein precursor, putative; GC: 42.37%; Transporter classification TC:3.A.1.15.2. Codon Adaptation Index (CAI): 0.786. LipoP prediction: SpII. SignalP prediction: Yes (prob. 1); Curator(s): P. Manque, J. Alves; Belongs to the bacterial solute-binding protein 9 family.
      
 0.438
ssaA
ABC-type Mn/Zn transporter, ATP-ase component, putative; GC: 45.47%; Transporter classification TC:3.A.1.15.2. Codon Adaptation Index (CAI): 0.783. Curator(s): P. Manque, J. Alves; Protein involved in nucleoside-triphosphatase activity.
      
 0.425
pstB1
Phosphate import ATP-binding protein pstB 1, putative; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
      
 0.421
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.