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nrdR protein (Pseudomonas putida W619) - STRING interaction network
"nrdR" - Transcriptional repressor NrdR in Pseudomonas putida W619
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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nrdRTranscriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (154 aa)    
Predicted Functional Partners:
ACA71072.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family (376 aa)
   
 
  0.975
ACA71074.1
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family (363 aa)
         
  0.885
nusB
Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons (166 aa)
 
   
  0.801
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family (319 aa)
   
   
  0.800
ACA71073.1
TIGRFAM- riboflavin synthase, alpha subunit; PFAM- Lumazine-binding protein; KEGG- pen-PSEEN0589 riboflavin synthase alpha chain (221 aa)
 
     
  0.799
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (915 aa)
 
   
  0.726
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5’-adenylate (BirA-bio- 5’-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon (321 aa)
 
     
  0.703
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family (170 aa)
   
   
  0.683
ACA71069.1
Methyltransferase type 12; PFAM- methyltransferase small; Methyltransferase type 12; KEGG- pen-PSEEN0585 hypothetical protein (219 aa)
              0.655
ACA71078.1
Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) (167 aa)
         
  0.653
Your Current Organism:
Pseudomonas putida W619
NCBI taxonomy Id: 390235
Other names: P. putida W619, Pseudomonas putida W619, Pseudomonas putida str. W619, Pseudomonas putida strain W619
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