STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pen:PSEEN4804 glutamate-1-semialdehyde aminotransferase. (427 aa)    
Predicted Functional Partners:
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.995
ACA72611.1
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.993
ACA74029.1
TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; Taurine catabolism dioxygenase TauD/TfdA; phosphopantetheine-binding; KEGG: pfo:Pfl_1846 peptide synthase.
 
 
 0.953
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.935
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
    
 0.896
ACA74025.1
TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: pen:PSEEN3229 pyoverdine sidechain peptide synthetase.
  
 
 0.866
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
   
 0.822
ACA74024.1
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: pap:PSPA7_2859 linear gramicidin synthetase subunit D.
  
 
 0.819
ACA71143.1
PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pen:PSEEN4802 phosphomethylpyrimidine kinase ThiD.
  
  
 0.797
ACA72113.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family.
 
   
 0.743
Your Current Organism:
Pseudomonas putida W619
NCBI taxonomy Id: 390235
Other names: P. putida W619, Pseudomonas putida str. W619, Pseudomonas putida strain W619
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