node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACA71143.1 | cysG | PputW619_0638 | PputW619_3403 | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pen:PSEEN4802 phosphomethylpyrimidine kinase ThiD. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.426 |
ACA71143.1 | hemL | PputW619_0638 | PputW619_0636 | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pen:PSEEN4802 phosphomethylpyrimidine kinase ThiD. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pen:PSEEN4804 glutamate-1-semialdehyde aminotransferase. | 0.797 |
ACA71143.1 | thiE | PputW619_0638 | PputW619_0637 | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pen:PSEEN4802 phosphomethylpyrimidine kinase ThiD. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
ACA72113.1 | ACA72611.1 | PputW619_1608 | PputW619_2111 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.876 |
ACA72113.1 | cysG | PputW619_1608 | PputW619_3403 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.961 |
ACA72113.1 | hemA | PputW619_1608 | PputW619_4457 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.773 |
ACA72113.1 | hemC | PputW619_1608 | PputW619_0256 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.986 |
ACA72113.1 | hemL | PputW619_1608 | PputW619_0636 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pen:PSEEN4804 glutamate-1-semialdehyde aminotransferase. | 0.743 |
ACA72611.1 | ACA72113.1 | PputW619_2111 | PputW619_1608 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. | 0.876 |
ACA72611.1 | cysG | PputW619_2111 | PputW619_3403 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.914 |
ACA72611.1 | hemA | PputW619_2111 | PputW619_4457 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.892 |
ACA72611.1 | hemC | PputW619_2111 | PputW619_0256 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.996 |
ACA72611.1 | hemL | PputW619_2111 | PputW619_0636 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pen:PSEEN4804 glutamate-1-semialdehyde aminotransferase. | 0.993 |
ACA74024.1 | ACA74025.1 | PputW619_3541 | PputW619_3542 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: pap:PSPA7_2859 linear gramicidin synthetase subunit D. | TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: pen:PSEEN3229 pyoverdine sidechain peptide synthetase. | 0.994 |
ACA74024.1 | ACA74029.1 | PputW619_3541 | PputW619_3546 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: pap:PSPA7_2859 linear gramicidin synthetase subunit D. | TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; Taurine catabolism dioxygenase TauD/TfdA; phosphopantetheine-binding; KEGG: pfo:Pfl_1846 peptide synthase. | 0.999 |
ACA74024.1 | hemL | PputW619_3541 | PputW619_0636 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: pap:PSPA7_2859 linear gramicidin synthetase subunit D. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pen:PSEEN4804 glutamate-1-semialdehyde aminotransferase. | 0.819 |
ACA74025.1 | ACA74024.1 | PputW619_3542 | PputW619_3541 | TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: pen:PSEEN3229 pyoverdine sidechain peptide synthetase. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: pap:PSPA7_2859 linear gramicidin synthetase subunit D. | 0.994 |
ACA74025.1 | ACA74029.1 | PputW619_3542 | PputW619_3546 | TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: pen:PSEEN3229 pyoverdine sidechain peptide synthetase. | TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; Taurine catabolism dioxygenase TauD/TfdA; phosphopantetheine-binding; KEGG: pfo:Pfl_1846 peptide synthase. | 0.999 |
ACA74025.1 | hemL | PputW619_3542 | PputW619_0636 | TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: pen:PSEEN3229 pyoverdine sidechain peptide synthetase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pen:PSEEN4804 glutamate-1-semialdehyde aminotransferase. | 0.866 |
ACA74029.1 | ACA74024.1 | PputW619_3546 | PputW619_3541 | TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; Taurine catabolism dioxygenase TauD/TfdA; phosphopantetheine-binding; KEGG: pfo:Pfl_1846 peptide synthase. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: pap:PSPA7_2859 linear gramicidin synthetase subunit D. | 0.999 |