STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (497 aa)    
Predicted Functional Partners:
ACA72082.1
TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: pen:PSEEN1713 aminopeptidase N.
  
 0.946
gshB
KEGG: pen:PSEEN5056 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family.
   
 
 0.945
ACA71282.1
Gamma-glutamyltransferase; KEGG: pen:PSEEN0716 gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
     
 0.912
ACA73544.1
Gamma-glutamyltransferase; KEGG: pfl:PFL_5184 gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
     
 0.912
gshA
TIGRFAM: glutamate--cysteine ligase; KEGG: pen:PSEEN0224 glutamate--cysteine ligase (gamma-glutamylcysteine synthetase) (gamma-ECS) (GCS); Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
 0.909
ACA75510.1
ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
 0.904
ACA74352.1
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pen:PSEEN4013 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
 0.833
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.828
glyA-2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.828
ACA74156.1
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: aba:Acid345_1980 cystathionine beta-lyase.
   
 
  0.801
Your Current Organism:
Pseudomonas putida W619
NCBI taxonomy Id: 390235
Other names: P. putida W619, Pseudomonas putida str. W619, Pseudomonas putida strain W619
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