node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACA72113.1 | ACA72611.1 | PputW619_1608 | PputW619_2111 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.876 |
ACA72113.1 | cysG | PputW619_1608 | PputW619_3403 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.961 |
ACA72113.1 | hemA | PputW619_1608 | PputW619_4457 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.773 |
ACA72113.1 | hemC | PputW619_1608 | PputW619_0256 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.986 |
ACA72113.1 | hemL | PputW619_1608 | PputW619_0636 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pen:PSEEN4804 glutamate-1-semialdehyde aminotransferase. | 0.743 |
ACA72611.1 | ACA72113.1 | PputW619_2111 | PputW619_1608 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. | 0.876 |
ACA72611.1 | cysG | PputW619_2111 | PputW619_3403 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.914 |
ACA72611.1 | gltX | PputW619_2111 | PputW619_1540 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.460 |
ACA72611.1 | hemA | PputW619_2111 | PputW619_4457 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.892 |
ACA72611.1 | hemC | PputW619_2111 | PputW619_0256 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.996 |
ACA72611.1 | hemL | PputW619_2111 | PputW619_0636 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pen:PSEEN4804 glutamate-1-semialdehyde aminotransferase. | 0.993 |
ACA74934.1 | cysG | PputW619_4454 | PputW619_3403 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: pen:PSEEN0878 molybdopterin biosynthesis MoeB protein. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.485 |
ACA74934.1 | hemA | PputW619_4454 | PputW619_4457 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: pen:PSEEN0878 molybdopterin biosynthesis MoeB protein. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.822 |
ACA74934.1 | murI | PputW619_4454 | PputW619_4453 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: pen:PSEEN0878 molybdopterin biosynthesis MoeB protein. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.808 |
ACA74934.1 | prfA | PputW619_4454 | PputW619_4456 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: pen:PSEEN0878 molybdopterin biosynthesis MoeB protein. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.820 |
ACA74934.1 | prmC | PputW619_4454 | PputW619_4455 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: pen:PSEEN0878 molybdopterin biosynthesis MoeB protein. | protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.808 |
cysG | ACA72113.1 | PputW619_3403 | PputW619_1608 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: psb:Psyr_2098 uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. | 0.961 |
cysG | ACA72611.1 | PputW619_3403 | PputW619_2111 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pfl:PFL_2290 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.914 |
cysG | ACA74934.1 | PputW619_3403 | PputW619_4454 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: pen:PSEEN0878 molybdopterin biosynthesis MoeB protein. | 0.485 |
cysG | gltX | PputW619_3403 | PputW619_1540 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.443 |