STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coiAPutative competence protein CoiA (fragment). (214 aa)    
Predicted Functional Partners:
mecA
Negative regulator of competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family.
  
  
 0.714
spx
Conserved hypothetical protein (ArsC family); Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
 
 
 0.711
Ldb0137
6 Protein of unknown function, without similarity to other proteins.
  
     0.682
Ldb0583
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.
 
     0.678
Ldb0584
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.
       0.669
ppnK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.669
Ldb0586
Pseudouridylate synthase.
       0.653
Ldb2081
6 Protein of unknown function, without similarity to other proteins.
  
     0.603
Ldb1432
Conserved hypothetical protein (ArsC family); Belongs to the ArsC family.
  
 
 0.586
Ldb1598
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.
  
     0.560
Your Current Organism:
Lactobacillus delbrueckii
NCBI taxonomy Id: 390333
Other names: L. delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus DSM 20081
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.