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ileS protein (Stenotrophomonas maltophilia R5513) - STRING interaction network
"ileS" - Isoleucine--tRNA ligase in Stenotrophomonas maltophilia R5513
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ileSIsoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily (943 aa)    
Predicted Functional Partners:
Smal_1124
Riboflavin biosynthesis protein; KEGG- xcb-XC_3088 bifunctional riboflavin kinase/FMN adenylyltransferase; TIGRFAM- riboflavin biosynthesis protein RibF; PFAM- FAD synthetase; Riboflavin kinase; Belongs to the ribF family (315 aa)
 
   
  0.978
pheT
KEGG- xcb-XC_1655 phenylalanyl-tRNA synthetase subunit beta; TIGRFAM- phenylalanyl-tRNA synthetase, beta subunit (802 aa)
   
 
  0.973
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family (174 aa)
 
   
  0.965
leuS
Leucine--tRNA ligase; TIGRFAM- leucyl-tRNA synthetase; KEGG- xcv-XCV2938 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family (880 aa)
 
 
0.947
valS
Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily (942 aa)
 
 
0.915
proS
Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction- proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as ’pretransfer’ editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated ’posttransfer’ editing and involves deacy [...] (567 aa)
   
 
  0.912
alaS
Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (882 aa)
 
 
  0.912
lysS
Lysine--tRNA ligase; TIGRFAM- lysyl-tRNA synthetase; PFAM- tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG- xac-XAC1876 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family (503 aa)
   
 
  0.903
cysS
Cysteine--tRNA ligase; KEGG- xcb-XC_1867 cysteinyl-tRNA synthetase; TIGRFAM- cysteinyl-tRNA synthetase; PFAM- Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family (458 aa)
 
   
  0.899
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1294 aa)
   
   
  0.888
Your Current Organism:
Stenotrophomonas maltophilia R5513
NCBI taxonomy Id: 391008
Other names: S. maltophilia R551-3, Stenotrophomonas maltophilia R551-3, Stenotrophomonas maltophilia R5513, Stenotrophomonas maltophilia str. R551-3, Stenotrophomonas maltophilia strain R551-3
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