STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smal_2960PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: xcv:XCV1394 ATP-dependent DNA ligase. (535 aa)    
Predicted Functional Partners:
Smal_2959
KEGG: xac:XAC1342 mRNA 3'-end processing factor.
 
 0.997
Smal_2962
PFAM: metallophosphoesterase; KEGG: xcv:XCV1392 putative phosphoesterase.
 
   
 0.963
Smal_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.961
Smal_2961
PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases; KEGG: xcv:XCV1393 ATP-dependent helicase.
 
    0.954
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.931
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
    
 0.916
Smal_0697
PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; KEGG: xcb:XC_3391 exodeoxyribonuclease IX.
  
 0.797
Smal_0878
KEGG: xcv:XCV1151 DNA polymerase III subunit delta'.
   
 0.735
Smal_2847
KEGG: pap:PSPA7_1392 hypothetical protein.
  
 0.732
hisB
Histidinol-phosphatase; KEGG: xcv:XCV1877 imidazole glycerol-phosphate dehydratase/histidinol phosphatase; TIGRFAM: histidinol-phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: imidazoleglycerol-phosphate dehydratase; Polynucleotide kinase 3 phosphatase central region; In the N-terminal section; belongs to the histidinol- phosphatase family.
   
 0.720
Your Current Organism:
Stenotrophomonas maltophilia R5513
NCBI taxonomy Id: 391008
Other names: S. maltophilia R551-3, Stenotrophomonas maltophilia R551-3, Stenotrophomonas maltophilia str. R551-3, Stenotrophomonas maltophilia strain R551-3
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