STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: xcb:XC_0892 glutamate-1-semialdehyde aminotransferase. (429 aa)    
Predicted Functional Partners:
Smal_3859
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: xcv:XCV4131 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.994
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.989
Smal_2272
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: pde:Pden_2564 amino acid adenylation domain.
  
 
 0.975
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.943
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
    
 0.932
hemF
Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
     
 0.737
Smal_0468
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; cytochrome c biogenesis protein transmembrane region; Redoxin domain protein; KEGG: rme:Rmet_1170 cytochrome c biogenesis protein, transmembrane region.
  
  
 0.674
Smal_1749
Aspartate kinase; KEGG: xcv:XCV1866 bifunctional aspartokinase/homoserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
  
 0.667
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.655
crcB
CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
      
 0.642
Your Current Organism:
Stenotrophomonas maltophilia R5513
NCBI taxonomy Id: 391008
Other names: S. maltophilia R551-3, Stenotrophomonas maltophilia R551-3, Stenotrophomonas maltophilia str. R551-3, Stenotrophomonas maltophilia strain R551-3
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