node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tmel_0045 | Tmel_0092 | Tmel_0045 | Tmel_0092 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein. | 0.467 |
Tmel_0045 | dnaJ | Tmel_0045 | Tmel_0087 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.525 |
Tmel_0045 | polA | Tmel_0045 | Tmel_1917 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.649 |
Tmel_0090 | Tmel_0091 | Tmel_0090 | Tmel_0091 | PFAM: General substrate transporter; major facilitator superfamily MFS_1. | PFAM: 3H domain protein; Helix-turn-helix, type 11 domain protein. | 0.831 |
Tmel_0090 | Tmel_0092 | Tmel_0090 | Tmel_0092 | PFAM: General substrate transporter; major facilitator superfamily MFS_1. | TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein. | 0.513 |
Tmel_0090 | Tmel_0093 | Tmel_0090 | Tmel_0093 | PFAM: General substrate transporter; major facilitator superfamily MFS_1. | PFAM: peptidylprolyl isomerase, FKBP-type. | 0.507 |
Tmel_0090 | dnaJ | Tmel_0090 | Tmel_0087 | PFAM: General substrate transporter; major facilitator superfamily MFS_1. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.545 |
Tmel_0090 | polA | Tmel_0090 | Tmel_1917 | PFAM: General substrate transporter; major facilitator superfamily MFS_1. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.539 |
Tmel_0091 | Tmel_0090 | Tmel_0091 | Tmel_0090 | PFAM: 3H domain protein; Helix-turn-helix, type 11 domain protein. | PFAM: General substrate transporter; major facilitator superfamily MFS_1. | 0.831 |
Tmel_0091 | Tmel_0092 | Tmel_0091 | Tmel_0092 | PFAM: 3H domain protein; Helix-turn-helix, type 11 domain protein. | TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein. | 0.512 |
Tmel_0091 | Tmel_0093 | Tmel_0091 | Tmel_0093 | PFAM: 3H domain protein; Helix-turn-helix, type 11 domain protein. | PFAM: peptidylprolyl isomerase, FKBP-type. | 0.507 |
Tmel_0091 | dnaJ | Tmel_0091 | Tmel_0087 | PFAM: 3H domain protein; Helix-turn-helix, type 11 domain protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.533 |
Tmel_0092 | Tmel_0045 | Tmel_0092 | Tmel_0045 | TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.467 |
Tmel_0092 | Tmel_0090 | Tmel_0092 | Tmel_0090 | TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein. | PFAM: General substrate transporter; major facilitator superfamily MFS_1. | 0.513 |
Tmel_0092 | Tmel_0091 | Tmel_0092 | Tmel_0091 | TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein. | PFAM: 3H domain protein; Helix-turn-helix, type 11 domain protein. | 0.512 |
Tmel_0092 | Tmel_0093 | Tmel_0092 | Tmel_0093 | TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein. | PFAM: peptidylprolyl isomerase, FKBP-type. | 0.779 |
Tmel_0092 | Tmel_0094 | Tmel_0092 | Tmel_0094 | TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein. | PFAM: major facilitator superfamily MFS_1. | 0.423 |
Tmel_0092 | dnaJ | Tmel_0092 | Tmel_0087 | TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.439 |
Tmel_0092 | polA | Tmel_0092 | Tmel_1917 | TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.564 |
Tmel_0093 | Tmel_0090 | Tmel_0093 | Tmel_0090 | PFAM: peptidylprolyl isomerase, FKBP-type. | PFAM: General substrate transporter; major facilitator superfamily MFS_1. | 0.507 |