STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sare_3900Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (351 aa)    
Predicted Functional Partners:
Sare_3901
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
 0.999
Sare_4566
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
 0.998
Sare_3902
PFAM: Hydratase/decarboxylase; KEGG: stp:Strop_3527 4-oxalocrotonate decarboxylase.
 
 
 0.996
Sare_4569
PFAM: Hydratase/decarboxylase; KEGG: bca:BCE_2155 2-hydroxypenta-2,4-dienoate hydratase, putative.
 
 
 0.983
Sare_3899
PFAM: Hydratase/decarboxylase; KEGG: stp:Strop_3524 4-oxalocrotonate decarboxylase.
 
  
 0.963
Sare_4567
Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
  
  
 
0.912
Sare_3903
PFAM: aldehyde dehydrogenase; KEGG: stp:Strop_3528 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
 0.839
Sare_3896
PFAM: amidohydrolase 2; KEGG: stp:Strop_3521 amidohydrolase 2.
 
   
 0.761
kmo
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
   
 
 0.743
Sare_1129
PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: stp:Strop_1239 3-isopropylmalate dehydrogenase.
  
 
 0.742
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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