STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)    
Predicted Functional Partners:
Sare_4675
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.991
Sare_4150
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: stp:Strop_3768 succinate dehydrogenase.
 
 0.983
Sare_1706
KEGG: stp:Strop_1709 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
 
 0.962
Sare_4174
Lactate/malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.962
Sare_2284
KEGG: stp:Strop_2136 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.959
Sare_1705
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: stp:Strop_1708 succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 0.952
Sare_4151
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; KEGG: stp:Strop_3769 succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 0.952
Sare_1406
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: stp:Strop_1448 malate dehydrogenase (oxaloacetate-decarboxylating).
 
 
 0.949
Sare_4075
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: stp:Strop_3695 malate dehydrogenase (oxaloacetate-decarboxylating).
 
 
 0.949
Sare_0511
PFAM: Citrate synthase; KEGG: stp:Strop_0423 citrate (Si)-synthase; Belongs to the citrate synthase family.
   
 0.924
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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