STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kmo-2Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (454 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
 0.986
kmo
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
  
  
 
0.910
Sare_4892
KEGG: stp:Strop_4418 hypothetical protein.
 
  
 0.837
Sare_4890
TIGRFAM: amino acid adenylation domain; thioester reductase domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; 3-beta hydroxysteroid dehydrogenase/isomerase; phosphopantetheine-binding; Male sterility domain; KEGG: stp:Strop_4416 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.791
Sare_4888
Methyltransferase type 12; PFAM: O-methyltransferase family 2; Methyltransferase type 12; KEGG: stp:Strop_4414 methyltransferase type 12.
 
     0.783
Sare_3896
PFAM: amidohydrolase 2; KEGG: stp:Strop_3521 amidohydrolase 2.
 
  
 0.779
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.
 
     0.779
Sare_4889
PFAM: major facilitator superfamily MFS_1; KEGG: stp:Strop_4415 major facilitator superfamily MFS_1.
       0.776
Sare_4891
TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: stp:Strop_4417 amino acid adenylation domain.
       0.773
Sare_4894
TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: stp:Strop_4420 amino acid adenylation domain.
       0.773
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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