node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bphy_0621 | Bphy_2809 | Bphy_0621 | Bphy_2809 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bxe:Bxe_A0344 porphobilinogen synthase; Belongs to the ALAD family. | 0.536 |
Bphy_0621 | hemA | Bphy_0621 | Bphy_2720 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.428 |
Bphy_0621 | hemC | Bphy_0621 | Bphy_2179 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.404 |
Bphy_0621 | hemL | Bphy_0621 | Bphy_0622 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bxe:Bxe_A0896 glutamate-1-semialdehyde-2,1-aminomutase. | 0.826 |
Bphy_1673 | Bphy_4038 | Bphy_1673 | Bphy_4038 | PFAM: condensation domain protein; KEGG: rpa:RPA3338 possible condensation domain, peptide synthetase. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: bpm:BURPS1710b_2088 pyoverdine synthetase D. | 0.588 |
Bphy_1673 | Bphy_4039 | Bphy_1673 | Bphy_4039 | PFAM: condensation domain protein; KEGG: rpa:RPA3338 possible condensation domain, peptide synthetase. | TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: bxe:Bxe_B0525 non-ribosomal peptide synthase. | 0.847 |
Bphy_1673 | hemL | Bphy_1673 | Bphy_0622 | PFAM: condensation domain protein; KEGG: rpa:RPA3338 possible condensation domain, peptide synthetase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bxe:Bxe_A0896 glutamate-1-semialdehyde-2,1-aminomutase. | 0.749 |
Bphy_2809 | Bphy_0621 | Bphy_2809 | Bphy_0621 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bxe:Bxe_A0344 porphobilinogen synthase; Belongs to the ALAD family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.536 |
Bphy_2809 | Bphy_3154 | Bphy_2809 | Bphy_3154 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bxe:Bxe_A0344 porphobilinogen synthase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: bxe:Bxe_B1649 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.854 |
Bphy_2809 | hemA | Bphy_2809 | Bphy_2720 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bxe:Bxe_A0344 porphobilinogen synthase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.872 |
Bphy_2809 | hemC | Bphy_2809 | Bphy_2179 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bxe:Bxe_A0344 porphobilinogen synthase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.996 |
Bphy_2809 | hemE | Bphy_2809 | Bphy_3023 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bxe:Bxe_A0344 porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.785 |
Bphy_2809 | hemL | Bphy_2809 | Bphy_0622 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bxe:Bxe_A0344 porphobilinogen synthase; Belongs to the ALAD family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bxe:Bxe_A0896 glutamate-1-semialdehyde-2,1-aminomutase. | 0.994 |
Bphy_3154 | Bphy_2809 | Bphy_3154 | Bphy_2809 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: bxe:Bxe_B1649 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bxe:Bxe_A0344 porphobilinogen synthase; Belongs to the ALAD family. | 0.854 |
Bphy_3154 | hemA | Bphy_3154 | Bphy_2720 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: bxe:Bxe_B1649 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.750 |
Bphy_3154 | hemC | Bphy_3154 | Bphy_2179 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: bxe:Bxe_B1649 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.972 |
Bphy_3154 | hemE | Bphy_3154 | Bphy_3023 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: bxe:Bxe_B1649 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.920 |
Bphy_3154 | hemL | Bphy_3154 | Bphy_0622 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: bxe:Bxe_B1649 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bxe:Bxe_A0896 glutamate-1-semialdehyde-2,1-aminomutase. | 0.694 |
Bphy_4038 | Bphy_1673 | Bphy_4038 | Bphy_1673 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: bpm:BURPS1710b_2088 pyoverdine synthetase D. | PFAM: condensation domain protein; KEGG: rpa:RPA3338 possible condensation domain, peptide synthetase. | 0.588 |
Bphy_4038 | Bphy_4039 | Bphy_4038 | Bphy_4039 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: bpm:BURPS1710b_2088 pyoverdine synthetase D. | TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: bxe:Bxe_B0525 non-ribosomal peptide synthase. | 0.943 |