node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bphy_0029 | Bphy_0932 | Bphy_0029 | Bphy_0932 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bxe:Bxe_A4423 putative 2-hydroxyacid dehydrogenase. | KEGG: bxe:Bxe_A2380 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.558 |
Bphy_0029 | serC | Bphy_0029 | Bphy_0740 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bxe:Bxe_A4423 putative 2-hydroxyacid dehydrogenase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.983 |
Bphy_0166 | Bphy_0932 | Bphy_0166 | Bphy_0932 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bxe:Bxe_A4269 putative 2-hydroxyacid dehydrogenase. | KEGG: bxe:Bxe_A2380 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.528 |
Bphy_0166 | Bphy_3184 | Bphy_0166 | Bphy_3184 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bxe:Bxe_A4269 putative 2-hydroxyacid dehydrogenase. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pol:Bpro_0422 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | 0.914 |
Bphy_0166 | serC | Bphy_0166 | Bphy_0740 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bxe:Bxe_A4269 putative 2-hydroxyacid dehydrogenase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.791 |
Bphy_0741 | Bphy_0743 | Bphy_0741 | Bphy_0743 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: bxe:Bxe_A0977 bifunctional, chorismate mutase/prephenate dehydratase. | PFAM: Prephenate dehydrogenase; KEGG: bxe:Bxe_A0979 bifunctional - 3-phosphoshikimate 1-carboxyvinyl transferase/prephenate dehydrogenase. | 0.988 |
Bphy_0741 | Bphy_0932 | Bphy_0741 | Bphy_0932 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: bxe:Bxe_A0977 bifunctional, chorismate mutase/prephenate dehydratase. | KEGG: bxe:Bxe_A2380 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.548 |
Bphy_0741 | Bphy_0978 | Bphy_0741 | Bphy_0978 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: bxe:Bxe_A0977 bifunctional, chorismate mutase/prephenate dehydratase. | KEGG: bxe:Bxe_A2331 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3. | 0.491 |
Bphy_0741 | aroA | Bphy_0741 | Bphy_0744 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: bxe:Bxe_A0977 bifunctional, chorismate mutase/prephenate dehydratase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.952 |
Bphy_0741 | gyrA | Bphy_0741 | Bphy_0738 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: bxe:Bxe_A0977 bifunctional, chorismate mutase/prephenate dehydratase. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.652 |
Bphy_0741 | serC | Bphy_0741 | Bphy_0740 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: bxe:Bxe_A0977 bifunctional, chorismate mutase/prephenate dehydratase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.968 |
Bphy_0743 | Bphy_0741 | Bphy_0743 | Bphy_0741 | PFAM: Prephenate dehydrogenase; KEGG: bxe:Bxe_A0979 bifunctional - 3-phosphoshikimate 1-carboxyvinyl transferase/prephenate dehydrogenase. | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: bxe:Bxe_A0977 bifunctional, chorismate mutase/prephenate dehydratase. | 0.988 |
Bphy_0743 | aroA | Bphy_0743 | Bphy_0744 | PFAM: Prephenate dehydrogenase; KEGG: bxe:Bxe_A0979 bifunctional - 3-phosphoshikimate 1-carboxyvinyl transferase/prephenate dehydrogenase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.993 |
Bphy_0743 | gyrA | Bphy_0743 | Bphy_0738 | PFAM: Prephenate dehydrogenase; KEGG: bxe:Bxe_A0979 bifunctional - 3-phosphoshikimate 1-carboxyvinyl transferase/prephenate dehydrogenase. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.432 |
Bphy_0743 | serC | Bphy_0743 | Bphy_0740 | PFAM: Prephenate dehydrogenase; KEGG: bxe:Bxe_A0979 bifunctional - 3-phosphoshikimate 1-carboxyvinyl transferase/prephenate dehydrogenase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.751 |
Bphy_0932 | Bphy_0029 | Bphy_0932 | Bphy_0029 | KEGG: bxe:Bxe_A2380 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bxe:Bxe_A4423 putative 2-hydroxyacid dehydrogenase. | 0.558 |
Bphy_0932 | Bphy_0166 | Bphy_0932 | Bphy_0166 | KEGG: bxe:Bxe_A2380 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bxe:Bxe_A4269 putative 2-hydroxyacid dehydrogenase. | 0.528 |
Bphy_0932 | Bphy_0741 | Bphy_0932 | Bphy_0741 | KEGG: bxe:Bxe_A2380 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: bxe:Bxe_A0977 bifunctional, chorismate mutase/prephenate dehydratase. | 0.548 |
Bphy_0932 | Bphy_3184 | Bphy_0932 | Bphy_3184 | KEGG: bxe:Bxe_A2380 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pol:Bpro_0422 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | 0.528 |
Bphy_0932 | pdxA | Bphy_0932 | Bphy_0398 | KEGG: bxe:Bxe_A2380 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.905 |