STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bphy_0773PFAM: NUDIX hydrolase; KEGG: bxe:Bxe_A1010 hypothetical protein. (235 aa)    
Predicted Functional Partners:
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
 0.875
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
    0.618
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
 0.594
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
   
 0.564
Bphy_2623
PFAM: ribonuclease II; KEGG: bxe:Bxe_A0538 putative ribonuclease II.
   
 0.564
rimM
16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
 
   0.531
cobD
Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
       0.512
Bphy_0013
PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: bte:BTH_II0214 ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family.
  
 0.492
rhlE
DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.
  
 0.492
Bphy_1367
PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: bxe:Bxe_A1652 putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.
  
 0.492
Your Current Organism:
Paraburkholderia phymatum
NCBI taxonomy Id: 391038
Other names: Burkholderia phymatum STM815, Burkholderia sp. STM815, P. phymatum STM815, Paraburkholderia phymatum STM815
Server load: low (24%) [HD]