node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bphy_0582 | Bphy_4730 | Bphy_0582 | Bphy_4730 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | KEGG: bxe:Bxe_B2108 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.903 |
Bphy_0582 | argG | Bphy_0582 | Bphy_5499 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | PFAM: argininosuccinate synthase; KEGG: bam:Bamb_5452 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. | 0.917 |
Bphy_0582 | purA | Bphy_0582 | Bphy_1409 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.931 |
Bphy_0582 | pyrB | Bphy_0582 | Bphy_2324 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: bte:BTH_I1465 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.915 |
Bphy_2576 | guaA | Bphy_2576 | Bphy_1312 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; KEGG: bxe:Bxe_A0593 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.818 |
Bphy_2576 | guaB | Bphy_2576 | Bphy_1314 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; KEGG: bxe:Bxe_A0593 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.813 |
Bphy_2576 | purA | Bphy_2576 | Bphy_1409 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; KEGG: bxe:Bxe_A0593 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.986 |
Bphy_2576 | purH | Bphy_2576 | Bphy_2553 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; KEGG: bxe:Bxe_A0593 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: bte:BTH_I1250 bifunctional purine biosynthesis protein PurH; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.985 |
Bphy_2576 | purL | Bphy_2576 | Bphy_1022 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; KEGG: bxe:Bxe_A0593 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.972 |
Bphy_2644 | guaA | Bphy_2644 | Bphy_1312 | PFAM: phosphoribosyltransferase; KEGG: bxe:Bxe_A0515 putative hypoxanthine phosphoribosyltransferase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.953 |
Bphy_2644 | guaB | Bphy_2644 | Bphy_1314 | PFAM: phosphoribosyltransferase; KEGG: bxe:Bxe_A0515 putative hypoxanthine phosphoribosyltransferase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.951 |
Bphy_2644 | purA | Bphy_2644 | Bphy_1409 | PFAM: phosphoribosyltransferase; KEGG: bxe:Bxe_A0515 putative hypoxanthine phosphoribosyltransferase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.945 |
Bphy_2644 | purH | Bphy_2644 | Bphy_2553 | PFAM: phosphoribosyltransferase; KEGG: bxe:Bxe_A0515 putative hypoxanthine phosphoribosyltransferase. | KEGG: bte:BTH_I1250 bifunctional purine biosynthesis protein PurH; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.938 |
Bphy_2644 | purL | Bphy_2644 | Bphy_1022 | PFAM: phosphoribosyltransferase; KEGG: bxe:Bxe_A0515 putative hypoxanthine phosphoribosyltransferase. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.522 |
Bphy_4730 | Bphy_0582 | Bphy_4730 | Bphy_0582 | KEGG: bxe:Bxe_B2108 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.903 |
Bphy_4730 | argG | Bphy_4730 | Bphy_5499 | KEGG: bxe:Bxe_B2108 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | PFAM: argininosuccinate synthase; KEGG: bam:Bamb_5452 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. | 0.908 |
Bphy_4730 | guaA | Bphy_4730 | Bphy_1312 | KEGG: bxe:Bxe_B2108 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.737 |
Bphy_4730 | guaB | Bphy_4730 | Bphy_1314 | KEGG: bxe:Bxe_B2108 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.510 |
Bphy_4730 | purA | Bphy_4730 | Bphy_1409 | KEGG: bxe:Bxe_B2108 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.937 |
Bphy_4730 | purL | Bphy_4730 | Bphy_1022 | KEGG: bxe:Bxe_B2108 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.709 |