STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bphy_27452-alkenal reductase; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: bxe:Bxe_A0412 putative exported serine protease, HtrA/AlgW-like; Belongs to the peptidase S1C family. (403 aa)    
Predicted Functional Partners:
Bphy_0835
PFAM: Anti sigma-E protein RseA family protein; KEGG: bxe:Bxe_A1079 anti sigma-E protein, RseA.
  
 
 0.727
Bphy_5175
PFAM: CheB methylesterase; MCP methyltransferase CheR-type; KEGG: reu:Reut_B5191 CheB methylesterase:MCP methyltransferase, CheR-type.
  
  
 0.701
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.663
Bphy_0135
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; KEGG: bxe:Bxe_B0221 multi-sensor hybrid histidine kinase.
  
  
 0.650
Bphy_2744
PFAM: protein of unknown function DUF34; KEGG: bch:Bcen2424_0440 protein of unknown function DUF34.
  
    0.615
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
 
 
 
 0.599
Bphy_3384
PFAM: NLP/P60 protein; KEGG: rso:RSc1695 probable phage HK022 GP19-related protein.
  
 0.579
Bphy_4210
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; CHASE3 domain protein; KEGG: bxe:Bxe_B1216 multi-sensor hybrid histidine kinase.
  
  
 0.513
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 
 0.500
rplY
Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
 
   0.499
Your Current Organism:
Paraburkholderia phymatum
NCBI taxonomy Id: 391038
Other names: Burkholderia phymatum STM815, Burkholderia sp. STM815, P. phymatum STM815, Paraburkholderia phymatum STM815
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