STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
betACholine dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (572 aa)    
Predicted Functional Partners:
betB
Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.
 
 
 0.983
Bphy_4241
PFAM: Aldehyde Dehydrogenase; KEGG: bxe:Bxe_B0183 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.908
Bphy_0350
Gluconate 2-dehydrogenase (acceptor); PFAM: cytochrome c class I; KEGG: bxe:Bxe_A4075 putative cytochrome c precursor.
  
 
 0.898
betI
Transcriptional regulator, TetR family; Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
 
  
 0.810
Bphy_5412
PFAM: phospholipase D/Transphosphatidylase; SNARE associated Golgi protein; KEGG: bps:BPSS1381 transmembrane phospholipase protein.
     
 0.803
Bphy_1546
KEGG: bxe:Bxe_A1415 non-hemolytic phospholipase C; TIGRFAM: phospholipase C, phosphocholine-specific; PFAM: phosphoesterase; protein of unknown function DUF756.
     
  0.800
psd
Phosphatidylserine decarboxylase related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
     
  0.800
Bphy_3755
PFAM: phosphoesterase; KEGG: bam:Bamb_3755 phospholipase C.
     
  0.800
Bphy_5255
PFAM: phosphatidylserine decarboxylase-related; KEGG: bxe:Bxe_C0076 putative phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family.
     
  0.800
Bphy_5529
PFAM: phosphoesterase; KEGG: bam:Bamb_5381 phosphoesterase.
     
  0.800
Your Current Organism:
Paraburkholderia phymatum
NCBI taxonomy Id: 391038
Other names: Burkholderia phymatum STM815, Burkholderia sp. STM815, P. phymatum STM815, Paraburkholderia phymatum STM815
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