node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABI63210.1 | prs | GbCGDNIH1_2312 | GbCGDNIH1_2314 | Hypothetical cytosolic protein. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.499 |
ABI63210.1 | pth | GbCGDNIH1_2312 | GbCGDNIH1_2317 | Hypothetical cytosolic protein. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.580 |
ABI63210.1 | rplY | GbCGDNIH1_2312 | GbCGDNIH1_2316 | Hypothetical cytosolic protein. | LSU ribosomal protein L25P; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.425 |
guaA | polA | GbCGDNIH1_1150 | GbCGDNIH1_1965 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.743 |
guaA | prfB | GbCGDNIH1_1150 | GbCGDNIH1_0280 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Bacterial peptide chain release factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.466 |
guaA | prs | GbCGDNIH1_1150 | GbCGDNIH1_2314 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.740 |
guaA | pth | GbCGDNIH1_1150 | GbCGDNIH1_2317 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.585 |
guaA | rplY | GbCGDNIH1_1150 | GbCGDNIH1_2316 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | LSU ribosomal protein L25P; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.413 |
guaA | tilS | GbCGDNIH1_1150 | GbCGDNIH1_1109 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | tRNA(Ile)-lysidine synthetase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.446 |
guaA | ychF | GbCGDNIH1_1150 | GbCGDNIH1_2318 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.712 |
mfd | polA | GbCGDNIH1_0836 | GbCGDNIH1_1965 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.602 |
mfd | prfB | GbCGDNIH1_0836 | GbCGDNIH1_0280 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Bacterial peptide chain release factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.726 |
mfd | pth | GbCGDNIH1_0836 | GbCGDNIH1_2317 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.626 |
mfd | tilS | GbCGDNIH1_0836 | GbCGDNIH1_1109 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | tRNA(Ile)-lysidine synthetase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.609 |
polA | guaA | GbCGDNIH1_1965 | GbCGDNIH1_1150 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.743 |
polA | mfd | GbCGDNIH1_1965 | GbCGDNIH1_0836 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.602 |
polA | prfB | GbCGDNIH1_1965 | GbCGDNIH1_0280 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Bacterial peptide chain release factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.426 |
polA | pth | GbCGDNIH1_1965 | GbCGDNIH1_2317 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.600 |
polA | ychF | GbCGDNIH1_1965 | GbCGDNIH1_2318 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.412 |
prfA | prfB | GbCGDNIH1_0606 | GbCGDNIH1_0280 | Bacterial peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Bacterial peptide chain release factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.815 |