STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (363 aa)    
Predicted Functional Partners:
ABP89633.1
Phosphoglycerate dehydrogenase and related dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.997
ABP90474.1
Phosphoserine phosphatase.
  
 
 0.954
ABP89249.1
Threonine synthase.
   
 0.940
ABP89402.1
O-acetylserine lyase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.933
ABP89632.1
Histone acetyltransferase HPA2 and related acetyltransferases.
     
 0.802
mnmE
Predicted GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
    
 0.783
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
  
 0.729
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
  
  
 0.717
ABP89634.1
Methylated DNA-protein cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.655
ABP89635.1
Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family.
       0.655
Your Current Organism:
Streptococcus suis 05ZYH33
NCBI taxonomy Id: 391295
Other names: S. suis 05ZYH33, Streptococcus suis str. 05ZYH33, Streptococcus suis strain 05ZYH33
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