STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacBRibose 5-phosphate isomerase RpiB. (171 aa)    
Predicted Functional Partners:
lacA
Ribose 5-phosphate isomerase RpiB.
 
 0.999
ABP90007.1
Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.985
lacG
Beta-glucosidase/6-phospho-beta- glucosidase/beta- galactosidase; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.982
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 
 0.929
glyA
Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
    0.923
lacD
Tagatose-1,6-bisphosphate aldolase; Belongs to the aldolase LacD family.
 
  
 0.917
ABP90011.1
Transcriptional regulator of sugar metabolism.
 
  
 0.889
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
  
 0.887
lacD-2
Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family.
 
  
 0.866
ABP89282.1
Uncharacterized protein conserved in bacteria; Belongs to the UPF0340 family.
 
  
 0.860
Your Current Organism:
Streptococcus suis 05ZYH33
NCBI taxonomy Id: 391295
Other names: S. suis 05ZYH33, Streptococcus suis str. 05ZYH33, Streptococcus suis strain 05ZYH33
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