STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABP90107.1Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase. (162 aa)    
Predicted Functional Partners:
ABP90108.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 0.999
ABP90109.1
Dihydropteroate synthase and related enzymes; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 0.999
folE
GTP cyclohydrolase I.
  
 0.997
ABP89107.1
Putative folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family.
 
  
 0.606
ABP89028.1
Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
  
 0.590
ABP90105.1
D-beta-hydroxybutyrate permease.
       0.556
birA
Biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.547
ABP90111.1
NTP pyrophosphohydrolase including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.
     
 0.542
ABP90671.1
Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.531
cca
tRNA nucleotidyltransferase/poly(A) polymerase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
    0.487
Your Current Organism:
Streptococcus suis 05ZYH33
NCBI taxonomy Id: 391295
Other names: S. suis 05ZYH33, Streptococcus suis str. 05ZYH33, Streptococcus suis strain 05ZYH33
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.