STRINGSTRING
KAOT1_12742 protein (Kordia algicida) - STRING interaction network
"KAOT1_12742" - Methylenetetrahydrofolate reductase in Kordia algicida
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KAOT1_12742Methylenetetrahydrofolate reductase (318 aa)    
Predicted Functional Partners:
KAOT1_12747
5-methyltetrahydrofolate--homocysteine methyltransferase (903 aa)
 
 
  0.994
KAOT1_12827
Uncharacterized protein (800 aa)
   
 
  0.952
KAOT1_09306
UDP-N-acetylglucosamine 1-carboxyvinyltransferase (815 aa)
   
 
  0.952
KAOT1_12752
Methionine synthase I, homocysteine S-methyltransferase (333 aa)
 
 
  0.950
folD
Bifunctional protein FolD ; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (292 aa)
   
 
  0.898
KAOT1_21162
Glycine dehydrogenase (aminomethyl-transferring) (948 aa)
   
 
  0.884
KAOT1_04982
Serine hydroxymethyltransferase ; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (424 aa)
   
 
  0.843
KAOT1_09321
Glycine cleavage system T protein ; The glycine cleavage system catalyzes the degradation of glycine (360 aa)
   
 
  0.823
KAOT1_15853
Cys/Met metabolism PLP-dependent enzyme superfamily protein (383 aa)
   
  0.813
KAOT1_12822
Uncharacterized protein (388 aa)
   
  0.813
Your Current Organism:
Kordia algicida
NCBI taxonomy Id: 391587
Other names: K. algicida, K. algicida OT-1, Kordia, Kordia Sohn et al. 2004, Kordia algicida, Kordia algicida OT-1, Kordia algicida Sohn et al. 2004, Kordia algicida str. OT-1, Kordia algicida strain OT-1
Server load: low (11%) [HD]