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gyrB protein (Pedobacter sp. BAL39) - STRING interaction network
"gyrB" - DNA gyrase subunit B in Pedobacter sp. BAL39
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
gyrBDNA gyrase subunit B ; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (652 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A ; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (869 aa)
  0.999
PBAL39_23527
DNA topoisomerase IV subunit A (1019 aa)
 
  0.982
PBAL39_21660
DNA polymerase III subunit beta ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (374 aa)
  0.902
PBAL39_06156
RNA polymerase sigma-70 factor ; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (286 aa)
 
 
  0.847
PBAL39_18429
RNA polymerase sigma-70 factor ; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (288 aa)
 
 
  0.844
PBAL39_19694
RNA polymerase sigma-70 factor ; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (286 aa)
 
 
  0.833
PBAL39_09306
Serine-tRNA synthetase (423 aa)
 
   
  0.831
dnaJ
Chaperone protein DnaJ ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (388 aa)
   
 
  0.788
dnaK
Heat shock protein 70 ; Acts as a chaperone (619 aa)
   
   
  0.761
PBAL39_09796
Protein translocase subunit SecA ; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (1103 aa)
   
 
  0.736
Your Current Organism:
Pedobacter sp. BAL39
NCBI taxonomy Id: 391596
Other names: P. sp. BAL39, Pedobacter BAL39, Pedobacter sp. BAL39
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