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leuA protein (Pedobacter sp. BAL39) - STRING interaction network
"leuA" - Alpha-isopropylmalate synthase in Pedobacter sp. BAL39
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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leuAAlpha-isopropylmalate synthase ; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (502 aa)    
Predicted Functional Partners:
leuB
Beta-IPM dehydrogenase ; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (363 aa)
 
  0.998
leuC
Isopropylmalate isomerase ; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (468 aa)
 
  0.997
leuD
Isopropylmalate isomerase ; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (194 aa)
 
 
  0.997
PBAL39_23257
Acetolactate synthase (579 aa)
 
 
  0.978
ilvD
Dihydroxy-acid dehydratase (565 aa)
 
 
  0.968
PBAL39_23247
Branched-chain amino acid aminotransferase (296 aa)
 
  0.951
PBAL39_23262
Acetohydroxyacid synthase small subunit (199 aa)
 
 
  0.945
PBAL39_09836
Branched-chain-amino-acid transaminase (355 aa)
   
  0.933
ilvA
Threonine deaminase ; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (416 aa)
   
   
  0.925
PBAL39_04833
Malic enzyme (767 aa)
     
 
  0.906
Your Current Organism:
Pedobacter sp. BAL39
NCBI taxonomy Id: 391596
Other names: P. sp. BAL39, Pedobacter BAL39, Pedobacter sp. BAL39
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