STRINGSTRING
EDM36031.1 protein (Pedobacter sp. BAL39) - STRING interaction network
"EDM36031.1" - COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit in Pedobacter sp. BAL39
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM36031.1COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit (1019 aa)    
Predicted Functional Partners:
EDM36036.1
DNA topoisomerase IV subunit B; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit (642 aa)
 
  0.937
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (652 aa)
 
  0.757
EDM34500.1
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (716 aa)
 
 
  0.749
argS
Arginine--tRNA ligase; COG0018 Arginyl-tRNA synthetase (591 aa)
 
   
  0.675
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (937 aa)
   
 
  0.674
EDM36641.1
COG3210 Large exoproteins involved in heme utilization or adhesion (1729 aa)
   
   
  0.659
EDM34053.1
Phenylalanine--tRNA ligase beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily (799 aa)
   
 
  0.652
lpxC
UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family (469 aa)
 
   
  0.604
EDM35047.1
COG0052 Ribosomal protein S2 (179 aa)
   
          0.601
EDM35242.1
annotation not available (148 aa)
   
     
  0.596
Your Current Organism:
Pedobacter sp. BAL39
NCBI taxonomy Id: 391596
Other names: P. sp. BAL39, Pedobacter sp. BAL39
Server load: low (12%) [HD]