STRINGSTRING
prfA protein (Pedobacter sp. BAL39) - STRING interaction network
"prfA" - Peptide chain release factor 1 in Pedobacter sp. BAL39
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prfAPeptide chain release factor 1 ; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (380 aa)    
Predicted Functional Partners:
PBAL39_02232
Putative protoporphyrinogen oxidase (288 aa)
 
  0.991
frr
Ribosome-releasing factor ; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (187 aa)
 
 
  0.899
rplM
50S ribosomal protein L13 ; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (147 aa)
 
 
  0.880
rplD
50S ribosomal protein L4 ; Forms part of the polypeptide exit tunnel (209 aa)
 
  0.870
lepA
Ribosomal back-translocase LepA ; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (595 aa)
 
   
  0.867
rplQ
50S ribosomal protein L17 (179 aa)
 
 
  0.842
PBAL39_09741
Peptide chain release factor 2 ; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (324 aa)
   
0.822
rplP
50S ribosomal protein L16 ; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (140 aa)
 
 
  0.808
mnmE
tRNA modification GTPase MnmE ; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (456 aa)
 
   
  0.792
PBAL39_06121
Peptide chain release factor (136 aa)
     
  0.791
Your Current Organism:
Pedobacter sp. BAL39
NCBI taxonomy Id: 391596
Other names: P. sp. BAL39, Pedobacter BAL39, Pedobacter sp. BAL39
Server load: low (8%) [HD]